PCR MSRE-qPCR for multiplexed analysis of DNA methylation
Kristi Kruusmaa discusses how a liquid biopsy-based analysis of methylation markers could aid in a timelier diagnosis and treatment of colorectal cancer. Methylation-Sensitive Restriction Enzyme (MSRE) -qPCR technology (MSRE-qPCR) enables detection of <10 copies of targets in highly multiplexed format, making it suitable for use in low tumour derived circulating DNA context.
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