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Digital Pathology in Drug Development: Opportunities and Challenges

We recently caught up with Dr Olulanu Aina, Scientific Director and Veterinary and Toxicological Pathologist at Janssen, about digital pathology applications in drug discovery...

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Gut-brain axis insights: why the microbiota holds therapeutic potential for neuro-developmental disorders

Evidence is emerging that there are important connections between the gut microbiome and neurodevelopmental disorders. In a guest post for World Autism Awareness Month this April, Chris Kenji Beer reviews recent discoveries.

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Probiotics save the gut microbiome from antibiotics

Antibiotics consumption is increasing worldwide, yet these therapies not only destroy pathogens but also damage our vital intestinal flora.

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Hafnia alvei HA4597™ – a new clinically validated solution in weight management

Hyperphagia is a common underlying cause of overweight and obesity. However, the dieting approaches towards weight loss are usually ineffective due to a persistent increase in appetite. Most of the current products in weight management are based on the principle of sugar/fat blockers and binders which has proven to be rather short-term solution.

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Making the microbiome accessible to millennials

In 2017 Lisa and Alanna MacFarlane started The Gut Stuff to bring gut health science and nutritional information together for the millennial generation. We spoke to Lisa about educating consumers and marketing products in gut health.

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4 ways to ensure probiotic quality that matters

Probiotics have been recommended for many conditions during the past century, ranging from long-term immunomodulatory effects to proven benefits in the management of chronic diseases. There is an increased availability of commercial products containing probiotic strains. Do all of them indeed provide health benefits for their consumers? I am convinced they don’t.

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Exploring the gut-brain axis in neurodevelopmental disorders

In the last decade, research has well established (relatively speaking) the impact of gut microbiota on host physiology and behaviour. We know that the gut and the brain communicate bidirectionally. The gut-brain axis includes nerval, endocrine and immunologic pathways. What is less well established is whether alterations in gut microbial composition can affect brain structure and function in neurodevelopmental disorders.

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Augustine Therapeutics: Bridging the Valley of Death with VIB Discovery Sciences

This article is republished with kind permission from BioVox.

Augustine Therapeutics is one of VIB’s latest spinoffs, developing a first-in-class drug for Charcot-Marie-Tooth disease. The company recently announced a seed-funding round of €4.2 million, led by V-Bio Ventures. We spoke to several of the key persons in Augustine about how the startup is tackling the “Valley of Death”: the no-man’s-land between academia and industry where many potential therapies often fail.

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