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  • Cross-Cultural Research into Microbiome Therapeutics for Cancer

    While microbiome therapeutics to support healthy gut function have garnered the lion’s share of attention, exciting approaches to oncology and anti-inflammatory therapeutics presage a new golden age for drug development.

  • Going Digital: A Norwegian Perspective on Pathology

    Inspired by the implementation of digital pathology in routine diagnostics in Sweden, Canada and the Netherlands, in Norway digitalisation projects are being organised. One of the pathologists working on these projects is Inger Nina Farstad.

  • Challenges and Applications in Using qPCR and Digital PCR for Environmental Samples

    Tiong Gim Aw’s investigation involves using NGS technology and metagenomics to study water security, microbial ecology and advanced biotechnology. His work examines new molecular methods for waterborne pathogens and source tracking techniques.

  • From PTI to ETI: An Overview of Plant Defence Response

    All plant cells are naturally exposed to bacteria and microbe colonisations. These can become pathogens when they invade the host cell to proliferate. However, successful penetration of the host cell is not an easy game.

  • Aflatoxin Binding by Probiotic Bacteria

    The health benefits of probiotics include the improvement of intestinal function, integrity and modulation of immunity. Furthermore, several studies have also suggested that probiotic bacteria and fermented dairy products possess anti-carcinogenic activity.

Molecular Beacons In Multiplex Digital PCR Assays

Every droplet of a digital PCR assay can contain as many as 35 different highly specific molecular beacon probes that are each tagged with a different combination of three out of seven available fluorescent colours.

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Managing Expectations with Digital Pathology

Anyone reading this would be familiar that in April the FDA determined after an extensive clinical trial that a whole slide imaging system presents no greater risk to patient care than an optical microscope. In a purely scientific study design, there is a null hypothesis that states “there is no significant difference between…” and then investigators try to prove or disprove that hypothesis.

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Finding a High Quality Probiotic

This article was originally published by the California Dairy Research Foundation, May 2017,  and is published with permission.

Among all the options for probiotics on store shelves, how can end-users spot a high-quality product? In today’s U.S. market, it’s not easy.

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Microfluidic Droplets on Demand

Active droplet generation in microfluidics is of high interest for a wide range of applications such as single cell analysis, DNA sequencing and nanoparticle synthesis to name a few.

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Potential Investments in Plant Microbiome

Among the topics covered during the panel discussion at the 5th Plant Genomics and Gene Editing Congress: Europe was the present and future investments of microbiome within the European market.

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Video: Streptococcus salivarius K12 BLIS in the Treatment of Oral Cavities and Otitis Media

Robert Osgood,  Program Director and Associate Professor at the Rochester Institute of Technology, was interviewed about his work on the oral probiotic, Streptococcus salivarius K12 BLIS.

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The future of precision medicine

Unreasonable cost of trial-and-error medicine means precision medicine is imperative for targeted therapies

Rising pressures to decrease healthcare cost globally, the emergence of value-based reimbursement models and healthcare digitisation trends are transitioning the medication model from ‘one-size-fits-all’ to stratified and outcome based targeted therapies.

Read More

Molecular Beacons In Multiplex Digital PCR Assays

Every droplet of a digital PCR assay can contain as many as 35 different highly specific molecular beacon probes that are each tagged with a different combination of three out of seven available fluorescent colours.

Read More

Managing Expectations with Digital Pathology

Anyone reading this would be familiar that in April the FDA determined after an extensive clinical trial that a whole slide imaging system presents no greater risk to patient care than an optical microscope. In a purely scientific study design, there is a null hypothesis that states “there is no significant difference between…” and then investigators try to prove or disprove that hypothesis.

Read More

Finding a High Quality Probiotic

This article was originally published by the California Dairy Research Foundation, May 2017,  and is published with permission.

Among all the options for probiotics on store shelves, how can end-users spot a high-quality product? In today’s U.S. market, it’s not easy.

Read More

Microfluidic Droplets on Demand

Active droplet generation in microfluidics is of high interest for a wide range of applications such as single cell analysis, DNA sequencing and nanoparticle synthesis to name a few.

Read More

Video: Streptococcus salivarius K12 BLIS in the Treatment of Oral Cavities and Otitis Media

Robert Osgood,  Program Director and Associate Professor at the Rochester Institute of Technology, was interviewed about his work on the oral probiotic, Streptococcus salivarius K12 BLIS.

Read More

The future of precision medicine

Unreasonable cost of trial-and-error medicine means precision medicine is imperative for targeted therapies

Rising pressures to decrease healthcare cost globally, the emergence of value-based reimbursement models and healthcare digitisation trends are transitioning the medication model from ‘one-size-fits-all’ to stratified and outcome based targeted therapies.

Read More

Innovative Research in Complementary and Alternative Medicines

Sydney, AU, Mon 13 FEB 2017; a television programme on the ABC aired a prime time expose on the Complementary and Alternative Medicines (CAM) industry, with the intent to discredit and warn consumers away from buying products that had no validated proof of working.

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Potential Investments in Plant Microbiome

Among the topics covered during the panel discussion at the 5th Plant Genomics and Gene Editing Congress: Europe was the present and future investments of microbiome within the European market.

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Report: Developing Biopesticides For Distribution

The application of crop biotechnology in agriculture has permitted an enhanced level of income to farmers and environmental benefits, while also reducing cropland expansion.

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Early And Present Applications Of CRISPR/Cas9

Genome editing technologies are a type of genetic engineering leading to the targeted modification of the genome of interest via the insertion, deletion or replacement of specific DNA sequences [1]. Amongst these, CRISPR/Cas9 is certainly the most promising and plant researchers have quickly realised its importance as its use is applied to several plant species [2, 3].

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A Focus On Genome Editing And Bioinformatics

During the 5th Plant Genomics and Gene Editing Congress, experts in the field of bioinformatics and genome sequencing shared their contributions in plant research. We made some of their presentation slides available for you to download.

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A Focus On Genome Engineering And Plant Microbiomes

Genetic and microbial engineering have shown to be key influencers on plant health. Discoveries in this field can help farmers to reduce reliance on agricultural chemicals and develop novel engineered crops which can better cope with climate change effects.

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From PTI To ETI: An Overview Of Plant Defence Response

All plant cells are naturally exposed to bacteria and microbe colonisations. These can become pathogens when they invade the host cell to proliferate [1].

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Ensuring Global Food Security: Genomic Approaches To Crop Diversity

As the world population is expected to reach 9 billion by 2050, global food security represents one of the most researched topics in plant science.

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CRISPR/Cas9 Technology in Rice and Wheat

Genome editing (GE) technologies comprise a set of molecular tools that lead to the targeted modification of a specific DNA sequence within the genome of interest.

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Challenges in Printing Hybrid Light Emitting Diodes

Organic Light Emitting Diodes (OLEDs)

Organic Light Emitting Diodes (OLEDs) are sub-micrometric devices formed by multi-stacked materials that have reached the appropriate Technological Readiness Level to be present in displays. Intense research has permitted the construction of diodes with long lifetimes, multi-colour emission and size variety.

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Enabling Flexible Displays and Sensors With Organic Electronics

While most conventional electronics are based on silicon transistors, there are other approaches being developed that seek to enable truly flexible components. At FlexEnable we believe the only way you can make truly flexible electronics is to start with truly flexible materials, so we use plastics (also referred to as organic materials) instead of ceramics to make our transistors.

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E-waste Recycling and Repurposing

Electronic waste (e-waste) is a fast growing problem. The UN estimates between 20-50 million tons of electronic waste is discarded every year, with only 12.5% of this being recycled. This leaves a colossal amount of e-waste sitting in landfill or improperly disposed of, which in turn leads to toxic materials leaching into the soil and water supply.

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Printed and Flexible Electronics: An Open Letter From Ton van Mol

Here at the Holst Centre, our technologies have matured in the last few years and our focus has expanded. We concentrate on application driven research, such as wearable health, automotive, the Internet of Things and solar energy.

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From Liquid Crystal Displays in 1996 to Microfluidics in 2016

Emmanuel Delamarche is a researcher at IBM Research who presented at our 2nd Microfluidics Congress about his research on precision diagnostics based on modular capillary-driven elements.

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