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  • What Kind Of Plant Genes Allow Crops To Shape The Rhizosphere Microbiota?

    Davide Bulgarelli tells us about the exciting work on barley microbiota currently underway in his lab.

  • How Do We Embed AI Into Digital Pathology Workflows?

    In this first of a two-part post, Liron Pantnowitz talks to us about embedding AI in Digital Pathology workflows.

  • Harnessing The Power Of RNA For A Healthy Gut Microbiome

    The healthy gut microbiome does exist at a functional level, but it needs a functional readout to find it.

  • Infographic: Application of Blockchain in Healthcare

    The infographic below presents a business case of blockchain application in addressing major data concerns in healthcare today

The EMA reflection paper on chronic liver disease and its implications for drug development in NASH

The European Medicines Agency published a “Reflection paper on chronic liver diseases (PBC, PSC, and NASH)” in Autumn 2018. Elmer Schabel gives a detailed display of the contents of this first regulatory guidance with regard to NASH, as well as a preliminary evaluation of the initial feedback and input received by stakeholders.

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How should healthcare stakeholders differentiate hype from reality with blockchain technology?

In my previous post, I discussed the likely applications of Blockchain technology in the short, medium, and long-term future. These applications follow on from the key strategic priorities necessitated by the healthcare industry’s trend towards digital decentralized care delivery models.

Read More

How do we build the solutions that will transform healthcare’s future?

We are building the solutions that will revolutionise healthcare in the future: solutions that will transform the trust relationship between the industry and patients, and the whole dynamic of healthcare. As co-founder of 23 Consulting, I am involved in supporting health organisations with their blockchain projects.

Read More

What Digital Pathology can learn from Radiology

Radiology is ahead of the curve because they’ve had CAD (Computer Aided Detection) for about 20 years. Radiology as a field has therefore had experience of introducing and integrating AI algorithms.

In my previous post, I talked about high-level cross imaging modalities. Here, I will discuss three challenges specific to pathology. I also work with Radiology imaging, and I think that comparisons between the two can help see how pathology might develop in the future.

Read More

A Finnish perspective on Blockchain adoption

The first topic I worked on that combined Blockchain and healthcare was the project I’m going to talk about at the Blockchain in Healthcare Congress. It was commissioned by the Finnish government, looking at how blockchain technology and Smart Contracts could help in a planned governmental social and healthcare reform. 

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Inhibiting NOX enzymes to treat multiple diseases with high medical need

NOX enzymes are a family of enzymes which amplify multiple signaling pathways associated with liver disease. At the Global NASH Congress, Alexandre Grassin shared a presentation about Genkyotex’s novel molecule GTK831, a NOX1/4 inhibitor, and the interim results from its phase two trial.

Read More

Four challenges in developing AI algorithms for medical imaging

Unsurprisingly, there is a lot of hype surrounding AI. Available deep learning packages make it so easy to create models and so we can expect lots of them to emerge. Anyone able to access sufficiently labelled data can start building models.

Read More

The top 4 challenges for microbiome companies – NIZO

Microbiome research is abundant and profoundly inspiring. Whether focusing on cancer drug response, or the more classical field of gut discomfort solutions, we are clearly on the brink of some long-anticipated breakthroughs. But despite the promise, companies in the field face challenges.

Read More

The EMA reflection paper on chronic liver disease and its implications for drug development in NASH

The European Medicines Agency published a “Reflection paper on chronic liver diseases (PBC, PSC, and NASH)” in Autumn 2018. Elmer Schabel gives a detailed display of the contents of this first regulatory guidance with regard to NASH, as well as a preliminary evaluation of the initial feedback and input received by stakeholders.

Read More

How should healthcare stakeholders differentiate hype from reality with blockchain technology?

In my previous post, I discussed the likely applications of Blockchain technology in the short, medium, and long-term future. These applications follow on from the key strategic priorities necessitated by the healthcare industry’s trend towards digital decentralized care delivery models.

Read More

How do we build the solutions that will transform healthcare’s future?

We are building the solutions that will revolutionise healthcare in the future: solutions that will transform the trust relationship between the industry and patients, and the whole dynamic of healthcare. As co-founder of 23 Consulting, I am involved in supporting health organisations with their blockchain projects.

Read More

What Digital Pathology can learn from Radiology

Radiology is ahead of the curve because they’ve had CAD (Computer Aided Detection) for about 20 years. Radiology as a field has therefore had experience of introducing and integrating AI algorithms.

In my previous post, I talked about high-level cross imaging modalities. Here, I will discuss three challenges specific to pathology. I also work with Radiology imaging, and I think that comparisons between the two can help see how pathology might develop in the future.

Read More

A Finnish perspective on Blockchain adoption

The first topic I worked on that combined Blockchain and healthcare was the project I’m going to talk about at the Blockchain in Healthcare Congress. It was commissioned by the Finnish government, looking at how blockchain technology and Smart Contracts could help in a planned governmental social and healthcare reform. 

Read More

Inhibiting NOX enzymes to treat multiple diseases with high medical need

NOX enzymes are a family of enzymes which amplify multiple signaling pathways associated with liver disease. At the Global NASH Congress, Alexandre Grassin shared a presentation about Genkyotex’s novel molecule GTK831, a NOX1/4 inhibitor, and the interim results from its phase two trial.

Read More

Four challenges in developing AI algorithms for medical imaging

Unsurprisingly, there is a lot of hype surrounding AI. Available deep learning packages make it so easy to create models and so we can expect lots of them to emerge. Anyone able to access sufficiently labelled data can start building models.

Read More

The top 4 challenges for microbiome companies – NIZO

Microbiome research is abundant and profoundly inspiring. Whether focusing on cancer drug response, or the more classical field of gut discomfort solutions, we are clearly on the brink of some long-anticipated breakthroughs. But despite the promise, companies in the field face challenges.

Read More

Using pathogen genome-informed strategies to understand the molecular mechanism plant disease

A key feature of our Congresses is the opportunity given to early career researchers to present their work.

At the upcoming 7th Plant Genomics & Gene Editing Congress: EuropeEgem Ozbudak will be one of four early career researchers to be given a 15-minute platform to present their work and receive a free registration pass for both days of the conference.

He will be discussing his research project on Colletotrichum acutatum, the causative agent of anthracnose crown and fruit rot, recognized as the second most important pathogen of strawberries on the globe due to its economic impacts.

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Developing Live Microbial Products with Science Driven Understanding

Günter Welz is part of the Open Innovation and Strategic Partnerships department at Bayer. He scouts for and builds relationships with external innovators in academia and business to enrich Bayer’s R&D pipeline, using various tools like the Open Innovation website and the venture capital arm.

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Bridging the policy-practice divide in genome-editing for agriculture

Regulation of emerging technology such as genome editing has mainly focused on responding to the consequences of innovation. The classical regulatory model of “identification-quantification-assessment-safety management” takes a risk-oriented approach to regulation of emerging technology and focuses on constraining the practice of science based on ethics, and administrative and risk management procedures.

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Navigating the European Court of Justice stance on GMOs

“The breeder’s dream is, of course, of an agency which would enable him to produce at will a particular kind of mutation uncontaminated by others which would merely be a nuisance to him….”

“There is as yet no indication from genetics of how, or even whether, this could be done… The dream of directed mutation as a tool in stock and crop improvement is still very much a dream”

These words were part of a lecture given by the well-known geneticist Kenneth Mather at the John Innes Institute in 1960. Now, after more than 50 years of research, his dream of directed mutation has become a reality.

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What kind of plant genes allow crops to shape the rhizosphere microbiota?

In my lab we aim to decipher the genetic basis of plant-microbe interactions taking place at the root-soil interface, in the so called “rhizosphere”. Microbes in this environment, collectively referred to as the rhizosphere microbiota, can enhance mineral mobilisation for plant uptake and crop protection, thereby representing a yet untapped resource for sustainable agriculture.

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Utilising Machine Learning Models to transform Plant Genomics

A lot of machine learning is used in technology such as Google Assistant, Amazon’s Alexa or Apple’s Siri, or to get rid of spam in your email inbox. Deep learning and rapid development of this technology enables us to solve image classification problems – e.g. “does this picture contain a dog or a cat?”. Also, artificial intelligence is set to soon replace many human jobs – in the darkest views, it might even pose an existential threat to the human race.

What repercussions do these developments have for genome-related research and in particular plant genomics?

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How CRISPR/Cas9 can help unravel Salt Stress Responses in Rice

Soil salinity affects a large amount of arable land and is one of the major causes of crop yield reduction worldwide. Rice, a major food crop feeding more than half of the world, is highly susceptible to salinity stress. Developing salt-stress tolerant rice cultivars is essential to sustain world rice production. The major focus of my research at the Maathuis Lab in the Biology Department of the University of York is looking for key players in the complex molecular networks responsible for rice salt-tolerance, and understanding their mode(s) of action.

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Integrating breeding technologies to supercharge future crops

The inspiration for the development of ‘Speed Breeding’ came from the first food product designed and purposefully bred for growing in space, a variety of wheat called USU-Apogee. Because there is not much space inside the spacecraft, they needed to maximise the number of wheat plants and grow them very quickly.

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Examining Blockchain Systems & Designing Smart Contracts

The blockchain has the potential to enable the collaboration between patients, researchers, and care providers to provide individualised care for patients, but how can this technology be harnessed in a practical way?

This was one of the key questions that was asked at the Blockchain in Healthcare Congress and we had the pleasure of welcoming an array of expert speakers from pharma, academia, and industry to provide the answer.

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The role of extrinsic motivation in sports and physical activity

Motivation is one of the most significant psychological concepts in many areas of life – from work and education to achieving personal goals. In sports and physical activity, motivation plays an especially important part due to the fact that, to millions of people worldwide, staying fit and active is not an obligation or a professional prerequisite, but rather a personal goal. Blockchain technology, together with elements of gamification, may actually help people achieve this goal.

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Conciliating Blockchain and GDPR

Aurélie Bayle is a Data Protection Officer at be-ys: a role she considers to be at the heart of the new legal framework for any company.

Before GDPR came into effect on 25th May 2018, she was working towards global compliance, which involved completing all the steps given by the Article 29 Data Protection Working Party, an advisory board made up of a representative from the data authority of each EU Member State, the European Data Protection Supervisor, and the European Commission. Her duties have included auditing the structures and processes, preparing the data protection impact assessments, checking the compliance of processing activities, analysing the risks of the processing in the medical area, preparing new processes and policies about data protection, and asking data processors about their own compliance.

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When Blockchain Meets the Right to be Forgotten: Technology Versus Law

Over the past few years, the popularity of the blockchain and cryptocurrencies has increased and has reached important notoriety, not only in scientific and IT journals, but also in the media. Although there are many kinds of cryptocurrencies in circulation nowadays, the most popular is Bitcoin.

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Supporting Blockchain Startups: An Open Letter from Katherine Merton

Dear colleagues,

The blockchain technology market is expected to grow to 2.3 billion US dollars by 2021, from 339.5 million US dollars in 2017. [1] With an annual growth rate of 61.5%, it is one of the fastest growing technologies in the healthcare industry.

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The Big List of Microfluidics Companies & Investors

The microfluidic-based devices market has been growing since 2014 due to the increasing point of care testing demand and the miniaturisation of microfluidic chips. 

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What will we do with all this data?

The amount of data we are creating every day has increased exponentially to match the rise in use of smart and connected devices. The internet of things has connected every aspect of our lives to the digital realm: most of these devices operate by tracking your habits, movements, preferences, voice, and more, then logging those habits online. Specifically, the collection of health data has become abundant, because most people now have or wear some sort of device to track daily patterns, steps, cycles, and more. Even our phones often default to track these things for us, whether we choose to enable the function or not.

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How Standards & Standardised Infrastructure Fuel Innovation

It might surprise a lot of people to learn that standards can be viewed as a tool to support innovation, to set businesses free and to focus on the core of their product where their expertise lie. When working with the use of electronic communication systems within the entire healthcare sector, the main focal point is often ensuring a good support for collaboration and work processes.

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