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  • Applications of Microfluidics in the Real World

    We examine some of the newest applications of microfluidics, including for environmental and clinical detection using paper-based devices, for detection of cancer markers using droplet digital microfluidics, and for assisted-reproductive technology.

  • The Role of Prebiotics and Probiotics in Aquaculture

    Research has shown that 76% of antibiotics used in aquaculture are for humans and six classes are on the WHO list of critically important antimicrobials. Their indiscriminate use in the last two decades has given rise to dire consequences.

  • CRISPR/Cas9 Technology in Rice and Wheat

    The most promising among the GE technologies, CRISPR/Cas9, was released as a biotechnological tool in 2012. Plant scientists were quick to understand the potential of this discovery and in 2013 three independent works applying CRISPR/Cas9 to various plant species were published on Nature Biotechnology.

  • The Changing Face of Pathology

    Laboratory medicine is in a state of flux right now. Not only are the tools needed to do the job evolving rapidly as technology advances, but the methods themselves and even the basic skills pathologists need are changing.

  • What Makes an iGEM Grand Prize Winner?

    The International Genetically Engineered Machine (iGEM) has recently opened its applications for the next round of competition and jamboree between student teams across the globe. The synthetic biology competition has steadily been growing in popularity since its launch.

Aflatoxin Binding by Probiotic Bacteria

The term ‘probiotic’ comes from the Greek words ‘προ’ and ‘βιοτος’, which mean ‘for life’. In 1953, the ‘probiotic’ term was introduced by Kollath as organic and inorganic supplements necessary to restore health to patients suffering a form of malnutrition resulting from eating too much highly refined food (Hamilton-Miller et al., 2003).

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Techniques in Transition

This article was originally published by The Pathologist, November 2016,  and is published with permission.

When it comes to “going digital,” pathologists fall into one of three groups: early adopters who are very enthusiastic, people in the middle who are unsure of its benefits, and those who are adamantly opposed to it (whose opinions range from skepticism to outright hostility).

Read More

Mushroom Polysaccharides: Promising Prebiotics for Healthy Gut Microbiota

Edible fungi or mushrooms are widely used as healthy food and nutraceutical products due to their high nutritive and medicinal value. The world production and consumption of edible and medicinal mushrooms has experienced a steady increase over the last few decades (>25-fold increase in 35 years from 1978  – 2012) and is projected to grow at 9.5% annually from 2014 to 2019, tripling the world GDP growth from 2013 – 2018 (2.5 – 3.0%).

Read More

Ensuring Global Food Security: Genomic Approaches To Crop Diversity

As the world population is expected to reach 9 billion by 2050, global food security represents one of the most researched topics in plant science.

Read More

Applications of microfluidics in the real world

We examine some of the newest applications of microfluidics, including for environmental and clinical detection using paper-based devices, for detection of cancer markers using droplet digital microfluidics, and for assisted-reproductive technology.

Read More

The Role of Prebiotics and Probiotics in Aquaculture

Physical, chemical and biological stresses are the order of the day for cultured fish. The expansion of aquaculture over the last three decades, which have stabilised and increased domestic and international demand for edible fish, means that farmers are increasing stocking densities and feed input per production unit.

Read More

CRISPR/Cas9 Technology in Rice and Wheat

Genome editing (GE) technologies comprise a set of molecular tools that lead to the targeted modification of a specific DNA sequence within the genome of interest.

Read More

The Changing Face of Pathology

This article was originally published by The Pathologist, November 2016,  and is published with permission.

Laboratory medicine is in a state of flux right now. Not only are the tools needed to do the job evolving rapidly as technology advances, but the methods themselves and even the basic skills pathologists need are changing.

Read More

Aflatoxin Binding by Probiotic Bacteria

The term ‘probiotic’ comes from the Greek words ‘προ’ and ‘βιοτος’, which mean ‘for life’. In 1953, the ‘probiotic’ term was introduced by Kollath as organic and inorganic supplements necessary to restore health to patients suffering a form of malnutrition resulting from eating too much highly refined food (Hamilton-Miller et al., 2003).

Read More

Techniques in Transition

This article was originally published by The Pathologist, November 2016,  and is published with permission.

When it comes to “going digital,” pathologists fall into one of three groups: early adopters who are very enthusiastic, people in the middle who are unsure of its benefits, and those who are adamantly opposed to it (whose opinions range from skepticism to outright hostility).

Read More

Mushroom Polysaccharides: Promising Prebiotics for Healthy Gut Microbiota

Edible fungi or mushrooms are widely used as healthy food and nutraceutical products due to their high nutritive and medicinal value. The world production and consumption of edible and medicinal mushrooms has experienced a steady increase over the last few decades (>25-fold increase in 35 years from 1978  – 2012) and is projected to grow at 9.5% annually from 2014 to 2019, tripling the world GDP growth from 2013 – 2018 (2.5 – 3.0%).

Read More

Applications of microfluidics in the real world

We examine some of the newest applications of microfluidics, including for environmental and clinical detection using paper-based devices, for detection of cancer markers using droplet digital microfluidics, and for assisted-reproductive technology.

Read More

The Role of Prebiotics and Probiotics in Aquaculture

Physical, chemical and biological stresses are the order of the day for cultured fish. The expansion of aquaculture over the last three decades, which have stabilised and increased domestic and international demand for edible fish, means that farmers are increasing stocking densities and feed input per production unit.

Read More

The Changing Face of Pathology

This article was originally published by The Pathologist, November 2016,  and is published with permission.

Laboratory medicine is in a state of flux right now. Not only are the tools needed to do the job evolving rapidly as technology advances, but the methods themselves and even the basic skills pathologists need are changing.

Read More

Microbiome Research and Development: An Open Letter From Karin Loser

Dear colleague,

The skin acts as an interface between the body and the external environment, protecting us from infections or toxins. It is also home to various microbial communities. The balance of commensal bacteria is indicative of healthy skin, with dysbiosis having been linked to various skin diseases, such as psoriasis. A high relative abundance of Actinobacteria has been detected in healthy human skin but inflammatory lesions from psoriasis patients are characterised by an over-representation of Proteobacteria and an under-representation of Actinobacteria.

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Making the move to 100 percent digital

This article was originally published by The Pathologist, November 2015, and is published with permission.

Digital pathology has been grabbing headlines lately as more and more labs explore its possibilities. It’s shown its merits for long-distance work, teaching and training, and expanding the capacity of overworked labs in need of time-saving techniques. But how far does the digital revolution go? At the Laboratory for Pathology East Netherlands (LabPON), we have taken a bold step into a computer-driven future – transitioning all of our manual diagnoses to digital.

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Ensuring Global Food Security: Genomic Approaches To Crop Diversity

As the world population is expected to reach 9 billion by 2050, global food security represents one of the most researched topics in plant science.

Read More

CRISPR/Cas9 Technology in Rice and Wheat

Genome editing (GE) technologies comprise a set of molecular tools that lead to the targeted modification of a specific DNA sequence within the genome of interest.

Read More

Applications of the CRISPR-System in Plant Resistance Breeding

Recent breeding strategies to improve crop resistance against pathogen attacks mainly rely on resistance genes. However, the genetic resource of resistance is limited in most crops, in particular in oilseed-rape (Brassica napus). However, breeding of resistance crops against new emerging diseases remains a great challenge.

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Future Applications of Setaria: An Open Letter From Tom Brutnell

Dear colleagues,

As Director of the Enterprise Institute for Renewable Fuels, I oversee many projects at the Donald Danforth Plant Science Center with the goal of developing new technologies that will drive sustainable energy production using bioenergy grasses, algae and oilseed crops.

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Stomata and Wounds: The Constant Dilemma of Pathogen Infection

Plant pests, together with abiotic stresses like drought, salinity and changes in temperature contribute to a constant loss in plant crops each year. Wound sites and stomata, represent the main entry pathogen sites.

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Modifying Plant Cell Walls to Produce Biofuels and Bioproducts

Biofuels and bioproducts are topics which have been particularly in vogue over the last decade. We spoke to Dr. Scheller who talked us through his findings on second-generation biofuels.

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Bridging The Gap: Developing An SNP Panel To Understand Genetic Diversity Of Modern Cannabis

At Phylos Bioscience we focus our research on understanding Cannabis genetic traits. I direct the data science aspects of our company, which includes the development of architecture for our automated analysis pipelines and statistical analysis of genetic variation data.

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Genomics – Where to Next?

Since January 2008, the cost of sequencing a human genome has outpaced Moore’s Law, which states that computing power doubles every two years. It now costs less than $1000 USD to sequence a human genome to a coverage of 30x.

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Challenges in Printing Hybrid Light Emitting Diodes

Organic Light Emitting Diodes (OLEDs)

Organic Light Emitting Diodes (OLEDs) are sub-micrometric devices formed by multi-stacked materials that have reached the appropriate Technological Readiness Level to be present in displays. Intense research has permitted the construction of diodes with long lifetimes, multi-colour emission and size variety.

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Enabling Flexible Displays and Sensors With Organic Electronics

While most conventional electronics are based on silicon transistors, there are other approaches being developed that seek to enable truly flexible components. At FlexEnable we believe the only way you can make truly flexible electronics is to start with truly flexible materials, so we use plastics (also referred to as organic materials) instead of ceramics to make our transistors.

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E-waste Recycling and Repurposing

Electronic waste (e-waste) is a fast growing problem. The UN estimates between 20-50 million tons of electronic waste is discarded every year, with only 12.5% of this being recycled. This leaves a colossal amount of e-waste sitting in landfill or improperly disposed of, which in turn leads to toxic materials leaching into the soil and water supply.

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Printed and Flexible Electronics: An Open Letter From Ton van Mol

Here at the Holst Centre, our technologies have matured in the last few years and our focus has expanded. We concentrate on application driven research, such as wearable health, automotive, the Internet of Things and solar energy.

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From Liquid Crystal Displays in 1996 to Microfluidics in 2016

Emmanuel Delamarche is a researcher at IBM Research who presented at our 2nd Microfluidics Congress about his research on precision diagnostics based on modular capillary-driven elements.

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