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  • The Race To Find A Treatment For NASH; What’s The Big Hold Up?

    In the next 2 years, NASH is set to overtake hepatitis C as the leading indication for liver transplantation, however there is no licensed treatment available worldwide.

  • Image Based Risk Assessment In Cancer

    Even in this age of modern molecular biology with gene and protein arrays, morphology remains a major contributor to diagnose disease and provide treatment guidelines.

  • Conciliating Blockchain And GDPR

    What is the data protection authority’s position on blockchain in the EU?

  • Genes, Food And The Environment

    Exploring the current challenges in microbiome analysis

  • How Effective Commercialisation Will Benefit Your AgTech Startup

    “In order to successfully commercialise your technology, it has to work in the hands of the farmer”.

Selecting a Formulation Type and Package Size for your Biopesticides

In the final instalment in our series of articles focusing on biopesticide product development, we will be discussing the importance of selecting a formulation type and package size, preferred packaging options, crop specific economics, tank mixability, and tank mixes.

Read More

Can Polyurethane Biomaterials Open a New Era in Tissue Engineering?

Tissue engineering/regenerative medicine (TERM) combines three-dimensional matrices, also known as scaffolds, cells and bioactive molecules (e.g. proteins, growth factors) to design functional constructs that have the capability to restore, maintain or improve the functionality of damaged tissues or whole organs.

Read More

The Potential of Probiotics for Human Health

This article was originally published in Health Europa Quarterly on 3 May 2018, and is published here with permission.

Johan van Hylckama Vlieg is the vice-president for microbiome and human health innovation at Chr. Hansen A/S, a global leading bioscience company that develops and produces cultures, enzymes, probiotics and natural colours for the food, nutritional, pharmaceutical and agricultural industries.

Speaking at the 5th Microbiome R&D & Business Collaboration Forum: Europe, van Hylckama Vlieg provided a valuable insight into some of the exciting potential application areas of probiotics.

Read More

Gaining Public Confidence in Genetically Modified Products

Despite the fact that GMs have been around for over thirty years, they still ignite debate. We spoke to Professor Jim Dunwell, University of Reading, at the 6th Plant Genomics & Gene Editing Congress: Europe to discuss the steps that should be taken to gain the public’s confidence.

Read More

Research and business opportunities in clinical microbiomics

This article was originally published in Health Europa Quarterly on 3 May 2018, and is published here with permission.

Exploring areas of research and development related to the microbiome – the collective name for the micro-organisms living in the human body – is the central topic of the annual Microbiome R&D Business Collaboration Forum. This year’s focus at the event was on business collaboration and private investment into research and development projects in the microbiome.

Read More

Dissecting gene expressions in nucleus versus cytoplasm with single-cell resolution

Single-cell ITP for physical fractionation of cytoplasmic versus nuclear nucleic acids (NAs)

Single-cell analyses have become powerful tools to explore the heterogeneity of cell populations such as tumours and developing embryos. Microfluidics have significantly contributed to this field, particularly to reduce the cost and improve the throughput of single-cell RNA sequencing and DNA sequencing.

Read More

How effective commercialisation will benefit your AgTech startup

Over the past thirty years, Donald R. Marvin, President and CEO of Concentric, has established an impressive track record for building exceptional value for stakeholders at several life science and agri-food companies. Formerly New Jersey’s CFO of the year, he has raised over $350 million in both private and public financing and completed nearly a dozen M&A transactions for his former companies.

Read More

Game Winning Hits: Singles or Home Runs?

To use a baseball analogy – there have been more games won with singles than with home runs. Home runs, when they happen, are spectacular, but they are few and far between. The journeyman single, while not the stuff of legend, gets the job done, and happens frequently. When it comes to the practical application of artificial intelligence in digital pathology, the analogy holds. The home run is machine diagnosis – replacement of the pathologist – the holy grail. The single represents baby steps which improve pathology practice, right up until the technology reaches its inevitable maturity.

Read More

Can Polyurethane Biomaterials Open a New Era in Tissue Engineering?

Tissue engineering/regenerative medicine (TERM) combines three-dimensional matrices, also known as scaffolds, cells and bioactive molecules (e.g. proteins, growth factors) to design functional constructs that have the capability to restore, maintain or improve the functionality of damaged tissues or whole organs.

Read More

The Potential of Probiotics for Human Health

This article was originally published in Health Europa Quarterly on 3 May 2018, and is published here with permission.

Johan van Hylckama Vlieg is the vice-president for microbiome and human health innovation at Chr. Hansen A/S, a global leading bioscience company that develops and produces cultures, enzymes, probiotics and natural colours for the food, nutritional, pharmaceutical and agricultural industries.

Speaking at the 5th Microbiome R&D & Business Collaboration Forum: Europe, van Hylckama Vlieg provided a valuable insight into some of the exciting potential application areas of probiotics.

Read More

Research and business opportunities in clinical microbiomics

This article was originally published in Health Europa Quarterly on 3 May 2018, and is published here with permission.

Exploring areas of research and development related to the microbiome – the collective name for the micro-organisms living in the human body – is the central topic of the annual Microbiome R&D Business Collaboration Forum. This year’s focus at the event was on business collaboration and private investment into research and development projects in the microbiome.

Read More

Dissecting gene expressions in nucleus versus cytoplasm with single-cell resolution

Single-cell ITP for physical fractionation of cytoplasmic versus nuclear nucleic acids (NAs)

Single-cell analyses have become powerful tools to explore the heterogeneity of cell populations such as tumours and developing embryos. Microfluidics have significantly contributed to this field, particularly to reduce the cost and improve the throughput of single-cell RNA sequencing and DNA sequencing.

Read More

Game Winning Hits: Singles or Home Runs?

To use a baseball analogy – there have been more games won with singles than with home runs. Home runs, when they happen, are spectacular, but they are few and far between. The journeyman single, while not the stuff of legend, gets the job done, and happens frequently. When it comes to the practical application of artificial intelligence in digital pathology, the analogy holds. The home run is machine diagnosis – replacement of the pathologist – the holy grail. The single represents baby steps which improve pathology practice, right up until the technology reaches its inevitable maturity.

Read More

The Updated List of Microbiome Companies and Investors

Since Global Engage’s first list of microbiome investors was released, the microbiome market has gone from strength-to-strength and is expected to grow from $289.411 million to $635.829 million by 2022. The major factors responsible for market growth include:

  • Increased risk of gut, autoimmune, inflammatory bowel, and skin health diseases
  • Lifestyle changes (eg. diet)
  • Ageing population

Read More

Presentation Slide Release: Cyber Security & Medical Devices

The Global Cyber Security in Healthcare & Pharma Summit 2018 brought together high-level representatives from around the globe to create a cyber security map for the future. If you weren’t able to make the conference, enjoy these slides from Caroline Rivett, Garvan Lynch and Katrine Vedel on securing medical devices and enabling better healthcare through cyber security.

Read More

The role of extrinsic motivation in sports and physical activity

Motivation is one of the most significant psychological concepts in many areas of life – from work and education to achieving personal goals. In sports and physical activity, motivation plays an especially important part due to the fact that, to millions of people worldwide, staying fit and active is not an obligation or a professional prerequisite, but rather a personal goal. Blockchain technology, together with elements of gamification, may actually help people achieve this goal.

Read More

Selecting a Formulation Type and Package Size for your Biopesticides

In the final instalment in our series of articles focusing on biopesticide product development, we will be discussing the importance of selecting a formulation type and package size, preferred packaging options, crop specific economics, tank mixability, and tank mixes.

Read More

Gaining Public Confidence in Genetically Modified Products

Despite the fact that GMs have been around for over thirty years, they still ignite debate. We spoke to Professor Jim Dunwell, University of Reading, at the 6th Plant Genomics & Gene Editing Congress: Europe to discuss the steps that should be taken to gain the public’s confidence.

Read More

How effective commercialisation will benefit your AgTech startup

Over the past thirty years, Donald R. Marvin, President and CEO of Concentric, has established an impressive track record for building exceptional value for stakeholders at several life science and agri-food companies. Formerly New Jersey’s CFO of the year, he has raised over $350 million in both private and public financing and completed nearly a dozen M&A transactions for his former companies.

Read More

Regulatory aspects of gene-edited crops: A Q&A with Jim Dunwell

On January 2018, Michal Bobek, in a preliminary judgement in a case at the European Court of Justice, advised that “organisms obtained by mutagenesis” should not be seen as genetically modified, unless they contained recombinant nuclear acid molecules or other GM organisms. [1]

Read More

The Future of Plant Gene Editing: A Q&A with Professor Richard Visser

We were delighted to welcome Richard Visser, Professor, Chair and Head of Plant Breeding, Dean of Research, Wageningen University & Research, to the 6th Plant Genomics and Gene Editing Congress, where he presented on the use of novel breeding techniques in practical breeding.

Read More

Using Machine Learning to Assign Gene Ontology

It is a quite common phenomenon in biology: we have identified a gene or a set of genes that are likely to be important for the system we are studying, but we have no clear explanation for why they are important or how they influence the system. For example, in plant genomics, we are often interested in a specific trait and have a genomic locus or a list of candidate genes that might affect this trait. The question is: how can we prioritise these genes in order to proceed to experimental validation?

To this end, it would be extremely useful if we knew the functions of our candidate genes. For instance, if a gene codes for an enzyme, what type of reaction does this enzyme catalyse? And in which pathways might this reaction take place?

Read More

Bringing your Biopesticides to Market

The application of crop biotechnology in agriculture has permitted an enhanced level of income to farmers and environmental benefits, while also reducing cropland expansion. Insect-protected crops, such as corn, showed more than 10% increase in yield worldwide and insect-protected corn and cotton augmented farm income by >$56 billion between 1996 and 2001.

There are important factors to consider to ensure the value and the benefits of these products. These relate to their mode of delivery from suppliers to end users, including correct shipping, storage as well as user education.

Read More

To regulate or not to regulate: Current legal status for gene-edited crops

Gene editing is the latest and sexiest DNA editing tool in the continuum of plant breeding innovations. With genetically modified organism (GMO) technology, scientists introduce “foreign” genes, i.e. genes from a different organism, into crops. With gene editing, scientists create additional genetic variation by making precise changes to the existing crop’s genome. It offers great opportunities, but also creates regulatory challenges.

Read More

Presentation Slide Release: Cyber Security & Medical Devices

The Global Cyber Security in Healthcare & Pharma Summit 2018 brought together high-level representatives from around the globe to create a cyber security map for the future. If you weren’t able to make the conference, enjoy these slides from Caroline Rivett, Garvan Lynch and Katrine Vedel on securing medical devices and enabling better healthcare through cyber security.

Read More

The role of extrinsic motivation in sports and physical activity

Motivation is one of the most significant psychological concepts in many areas of life – from work and education to achieving personal goals. In sports and physical activity, motivation plays an especially important part due to the fact that, to millions of people worldwide, staying fit and active is not an obligation or a professional prerequisite, but rather a personal goal. Blockchain technology, together with elements of gamification, may actually help people achieve this goal.

Read More

Conciliating Blockchain and GDPR

Aurélie Bayle is a Data Protection Officer at be-ys: a role she considers to be at the heart of the new legal framework for any company.

Before GDPR came into effect on 25th May 2018, she was working towards global compliance, which involved completing all the steps given by the Article 29 Data Protection Working Party, an advisory board made up of a representative from the data authority of each EU Member State, the European Data Protection Supervisor, and the European Commission. Her duties have included auditing the structures and processes, preparing the data protection impact assessments, checking the compliance of processing activities, analysing the risks of the processing in the medical area, preparing new processes and policies about data protection, and asking data processors about their own compliance.

Read More

When Blockchain Meets the Right to be Forgotten: Technology Versus Law

Over the past few years, the popularity of the blockchain and cryptocurrencies has increased and has reached important notoriety, not only in scientific and IT journals, but also in the media. Although there are many kinds of cryptocurrencies in circulation nowadays, the most popular is Bitcoin.

Read More

Supporting Blockchain Startups: An Open Letter from Katherine Merton

Dear colleagues,

The blockchain technology market is expected to grow to 2.3 billion US dollars by 2021, from 339.5 million US dollars in 2017. [1] With an annual growth rate of 61.5%, it is one of the fastest growing technologies in the healthcare industry.

Read More

The Big List of Microfluidics Companies & Investors

The microfluidic-based devices market has been growing since 2014 due to the increasing point of care testing demand and the miniaturisation of microfluidic chips. 

Read More

What will we do with all this data?

The amount of data we are creating every day has increased exponentially to match the rise in use of smart and connected devices. The internet of things has connected every aspect of our lives to the digital realm: most of these devices operate by tracking your habits, movements, preferences, voice, and more, then logging those habits online. Specifically, the collection of health data has become abundant, because most people now have or wear some sort of device to track daily patterns, steps, cycles, and more. Even our phones often default to track these things for us, whether we choose to enable the function or not.

Read More

How Standards & Standardised Infrastructure Fuel Innovation

It might surprise a lot of people to learn that standards can be viewed as a tool to support innovation, to set businesses free and to focus on the core of their product where their expertise lie. When working with the use of electronic communication systems within the entire healthcare sector, the main focal point is often ensuring a good support for collaboration and work processes.

Read More

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