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Agricultural Biotechnology

Case Study: High-throughput SNP Screening Downstream of CRISPR/Cas9 Gene Editing

One of the most powerful applications of genome editing is the introduction of nucleotide substitutions in specific genomic sites. This can be used to mimic single-nucleotide polymorphisms (SNPs) or to generate stop codons that yield precise gene knockouts. However, screening hundreds of clones for a single edited nucleotide remains a challenge, especially in the absence of a corresponding phenotype.

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Challenges of epigenetic studies in plants: focus on ChIP technique

Agnieszka Zelisko-Schmidt from Diagenode elaborates on their poster presented at the 6th Plant Genomics & Gene Editing Congress: Europe, explaining how regulatory pathways in plants can be unravelled using the universal plant ChIP-seq kit.

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Increasing Shelf Life of Perishable Produce Using Patented Gene Technology

The eIF‑5A protein is highly conserved in all plants and animals and is the only protein in any organism that has the unique hypusine modification caused by the Deoxyhypusine Synthase (DHS) enzyme. The unmodified-to-hypusinated ratio of these two forms of eIF‑5A determines the fate of the cell. Recent studies suggest that eIF‑5A is mainly involved in RNA metabolism and movement through the cell, thereby regulating cell growth, proliferation, and programmed death. These stable genetic changes will significantly enhance crop traits, including:

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An Updated Round-Up of the Top Plant Genome Databases

There’s more plant genome databases than there ever has been before. We’ve collated the most recent databases for ontology information on a variety of crops, including: rice, maize, wheat, sorghum, barley, millet, rye, and oats.

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EU Court of Justice Rules that Gene Edited Organisms will be Regulated as GMOs

On 25 July 2018, the Court of Justice of the European Union, the EU’s highest court, issued a decision clarifying whether the EU would regulate products of innovative breeding techniques, like gene editing, under the EU’s Directive 2001/18, the principal EU law governing the regulation of GMOs.

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Regulating Biostimulant Products

Degrading soil quality and increased interest in sustainable farming have caused the biostimulant market to go from strength-to-strength and it is expected to reach $4.14 billion by 2025. [1] Despite this, companies have expressed concerns that the regulation of biostimulants will hinder industry growth and the longevity of small companies and start-ups.

We spoke to Nick Moon, Global Regulatory Manager, Plant Impact, to discuss the regulation of biostimulants and its impact on industry.

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Transcriptomic Profiling of Pearl Millet for Salinity Stress Response

In an article which discussed the exploration of the ‘orphan crop’ pearl millet, Amibka Dudhate concluded that photosynthesis, plant hormone signal transduction, and mitogen-activated protein kinase signalling pathways are significantly activated on the advent of drought stress in pearl millet. Her colleague, Harshraj Shinde, expands on these findings.

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Unraveling the Regulatory Quagmire of Agrobiologicals

At the Partnerships in Biocontrol, Biostimulants, & Microbiome: Europe, Peter Jens, Director of Strategic Alliances at Koppert Biological Systems and CEO of AND Biopharma, discussed regulation from product to systems thinking.

He focused specifically on the way in which consumers and citizens have become more vocal on the quality of products, arguing that the current regulatory discussion is fated and different thinking is required.

Here, he explains what he means by ‘different’ kinds of thinking and how this could help unravel the regulatory quagmire of agrochemicals and agrobiologicals.

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