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Medicinal Chemistry

Why drug designers will be at a disadvantage without AI

We spoke to John Griffin, CSO at Numerateto find out how AI is changing drug discovery and development. Numerate is a drug design company applying cutting-edge AI to transform the process of small molecule drug design.

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Controlling the fate of cancer cells with SF3B1 modulators

Andrew Cook has worked in the pharmaceutical industry for over 20 years. Throughout his career, he has endeavoured to do things differently, a little out of the ordinary, leading him to his work at H3 Biomedicine on splice modulators. “Part of the reason it attracted me” he says, “is it’s so different. It’s a natural product-based drug discovery effort, and I had never done that before”.

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Integrating AI and HCI for drug discovery

Bringing new therapeutics to patients is easier said than done due to the enormous intrinsic complexity behind being efficacious and safe.

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Why NOW for Targeting RNA with Small Molecules?

Before tackling the question of why everyone thinks drugging RNA is so hard, one might ask why drugging proteins is considered to be so easy (at least by comparison). Put differently, why were proteins first?

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Accelerating the Medicinal Chemistry Design Cycle

MedChemNet and Future Medicinal Chemistry editors Jasmine Harris and Ben Walden interviewed Emma Parmee from Merck & Co at the Global Medicinal Chemistry and GPCR Summit.

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Optimising Targeted Protein Degradation

02MedChemNet and Future Medicinal Chemistry editors Jasmine Harris and Ben Walden interviewed George Burslem from Yale University at the Global Medicinal Chemistry and GPCR Summit.

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Insights in Medicinal Chemistry and GPCR

MedChemNet and Future Medicinal Chemistry editors Jasmine Harris and Ben Walden share 5 key insights gained from the Global Medicinal Chemistry and GPCR Summit.

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Reviewing the Global Medicinal Chemistry and GPCR Summit

MedChemNet and Future Medicinal Chemistry were thrilled to attend the Global Medicinal Chemistry and GPCR Summit, organised by Global Engage. The event shared the latest in medicinal chemistry and GPCR developments with delegates from across the globe. Represented at the summit were a number of large and small pharmaceutical companies, as well as biotechnology companies, CROs and academics.

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