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Microbiome

Increasing plant protein digestion in an in vitro model

Population increases and patterns of consumption will put pressure on animal protein supply and price over the coming decades. Plant proteins are a viable alternative, but have a lower digestibility then animal proteins.

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Microbiome R&D & Business Collaboration Forum presentation slides

Following the Microbiome R&D & Business Collaboration Forum, we have made the following presentation slides from Karoline Faust, Dirk Hadrich, Lesley Hoyles & Jos Seegers available.

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FMT-based discovery: from platform to product

Fecal microbiota transplant (FMT) is probably the microbiome based therapy that has received the most media attention. It seems journalists love to talk about poo.

This has given momentum to research in the field. As the amount of trial data and fear of antibiotic resistance grows, FMT is now a much more common treatment for conditions like clostridioides difficile infection (CDI).

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The Skin Microbiome & Cosmeceuticals Congress presentation slides

Following the Skin Microbiome & Cosmeceuticals Congress: Europe, we have made the following presentation slides from Richard Andrews, Ingmar Claes, Marie Drago & Maya Ivanjesku available.

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The top 4 challenges for microbiome companies – NIZO

Microbiome research is abundant and profoundly inspiring. Whether focusing on cancer drug response, or the more classical field of gut discomfort solutions, we are clearly on the brink of some long-anticipated breakthroughs. But despite the promise, companies in the field face challenges.

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Discovering the dynamics of prophage induction in the gut ecosystem

The human gut is a complex ecosystem dominated by bacteria and their viruses, i.e. phages. Approximately half of the viruses that reside in our intestine are derived from lysogens, bacteria that contain normally dormant viruses – prophages — in their genome.

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A new phage in Microbiome discovery

The Human Genome Project was the largest collaborative scientific project that is credited with transforming our understanding of human genetics and revolutionizing medical research. It’s completion in 2003 was greeted as a watershed moment in the history of scientific discovery.

Today, a much less heralded collaborative scientific project is underway that may have implications for human health that could be as profound as that of the Human Genome Project. The Human Microbiome Project (HMP) is a National Institutes of Health (NIH)-supported collaboration that develops “research resources to enable the study of the microbial communities that live in and on our bodies and the roles they play in human health and disease”.

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Harnessing microfluidics for high throughput microbiology R&D

The BioMillenia technology platform is based on microfluidics, a technology platform widely used in life sciences, but not necessarily in microbiology. There are some commercial developments of the technology, for example NGS or dPCR platforms, but it’s a very new application in the field of microbiology.

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