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NASH

NASH – The Silent Killer You’ve Never Heard Of

Silent killers such as diabetes, high cholesterol and hypertension have been well discussed for many years. While non-medical professionals may not understand the pathophysiology of these diseases, most people can appreciate that they are harmful conditions which require treatment. Worldwide, nonalcoholic fatty liver disease (NAFLD) is estimated to affect more than 1 billion people; so why is nobody talking about it?

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Lifestyle Interventions in NASH – Backbone, Therapy or Waste of Time?

The effects of lifestyle interventions as a baseline therapy for the treatment of NASH are well accepted. However, there is a high degree of frustration when it comes to recommending and implementing lifestyle changes. Large interventional studies in the field of metabolic disease are largely negative with regards to long-term outcomes.

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Hacking Metabolism to Treat NAFLD

Multifactorial diseases require a safe, multifunctional and integrated approach to treatment. Based on this recognition, a new class of therapeutics, called Defined Amino Acid Compositions (DAACs™), are being pioneered by Axcella Health.

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