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Precision Medicine

Personalised Cancer Vaccines for Mesothelioma

Immunotherapy continues to gain popularity in several areas related to cancer research and new treatments. Studies prove that each and every cancer case is unique, so the need for personalised medicine presents a logical focus. Personalised cancer vaccines are one form of cancer immunotherapy. The vaccines are a form of precision medicine, which has become an increasingly more enticing area for treatment research.

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Pricing Pressure, Payer Perspectives and Innovative Diagnostic Platforms

We spoke to Alex Bastian about how he got started in precision medicine, where he sees it going and how he intends to use real world evidence to unlock the potential around personalised approaches to drug development:

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What’s been happening in precision medicine this month?

There has been some interesting news, discoveries and development to catch up on this month in the world of precision medicine. Take a look at the list below to find out more:

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The Challenges & Considerations of Reporting Somatic Variants in Cancer

Industrial and “omic” scale mutational profiling of solid tumours are possible as a result of massively parallel sequencing technology. However, these clinical genomic testing capabilities have also brought myriad new biological, technical and operational challenges not encountered in monogenic disorder testing. All of this impacts the interpretation and reporting of somatic variants. As a testament to the nascency of this field, the first published consensus guidelines for interpretation of variants in cancer was only released in early 2017.

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Large-Scale Genetics Research: Q&A with Aris Baras

With genetic data making headlines, Aris Baras reflects on how genetic research can further advancements in medicine and delves into how his team’s work on large-scale approach is paving the way for new discoveries and enhanced patient care.

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Precision Medicine and Companion Diagnostics in Stroke Patients

A stroke is a clinical condition that could benefit greatly from personalized medicine. Strokes remain a leading cause of mortality and morbidity in the United States, affecting over 800,000 adults annually, leaving many with a permanent disability. The current stroke population are approximately 195,000 recurrent strokes, which are often more severe, debilitating, and costly than first-time strokes.

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Immunotherapy for Malignant Mesothelioma

The current field of cancer research is seeing gains in almost every aspect of care, from the foundations of the disease to the development of successful treatment. With increased funding and attention to oncology care, immunotherapy and precision medicine are among the most promising patient-centred areas of current research and translational medicine.

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Precision Medicine in Rare Diseases

7% of the population will be affected by a rare disease at some point in their lives. In anticipation of the Precision Medicine & Biomarkers Leaders Summit: USA and in recognition of Rare Disease Day, we have collated some of the top articles on rare diseases and their treatments.

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