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Precision Medicine

Is the age of invention over?

At the dawn of the last century, people who were heralded as world-changers were a different breed. Edison, Franklin (and let’s also put Tesla here, though his contributions weren’t recognized at the time), Turing, Neumann, and a lot of other great people. Things are different now. The people we idolize today are the innovators – Jobs, Musk, Page&Brin – the Great Communicators who can drive products to the market, and carve out a viable market strategy despite the strong competition, or create entirely new markets.

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Precision Medicine: An open letter from Miro Venturi

Dear Colleagues,

In recent times, we have seen advances in precision medicine lead to powerful discoveries and improved patient care. Liquid biopsies for example, now have the potential to be a real game-changer in cancer testing and could revolutionise cancer care.

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The future of precision medicine

Unreasonable cost of trial-and-error medicine means precision medicine is imperative for targeted therapies

Rising pressures to decrease healthcare cost globally, the emergence of value-based reimbursement models and healthcare digitisation trends are transitioning the medication model from ‘one-size-fits-all’ to stratified and outcome based targeted therapies.

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Upcoming Developments in Precision Medicine

Future of immunotherapies

Immunotherapies are on the fast growth trajectory which will be moderated based on responder groups, toxicity and efficacy results and high costs and increasingly used in combination therapies. The overall immune oncology checkpoint inhibitor market was over $2.0 billion and is set to grow to $14 billion by 2018.

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Presidents, Rock Stars and Companion Diagnostics

President Jimmy Carter announced last spring that he no longer needed treatments for the metastatic melanoma found in his brain – after treatment with pembrolizumab (Keytruda, Merck), his physicians could no longer detect the cancer.

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New Developments in Liquid Biopsy Technology

Advances in liquid biopsy technology have seen the development of novel methods that allow for different applications in genetic disorders and tumour detection.

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Development of ecosystems for precision medicine

The genomic and post-genomic age promises much for clinical medicine, largely because we can now comprehensively sequence genomic DNA to identify polymorphisms, patterns and mutations. We can also measure gene expression routinely and systematically and with high sensitivity measure the amounts of proteins produced.

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