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Tag: genome

Bridging the policy-practice divide in genome-editing for agriculture

Regulation of emerging technology such as genome editing has mainly focused on responding to the consequences of innovation. The classical regulatory model of “identification-quantification-assessment-safety management” takes a risk-oriented approach to regulation of emerging technology and focuses on constraining the practice of science based on ethics, and administrative and risk management procedures.

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Using Machine Learning to Assign Gene Ontology

It is a quite common phenomenon in biology: we have identified a gene or a set of genes that are likely to be important for the system we are studying, but we have no clear explanation for why they are important or how they influence the system. For example, in plant genomics, we are often interested in a specific trait and have a genomic locus or a list of candidate genes that might affect this trait. The question is: how can we prioritise these genes in order to proceed to experimental validation?

To this end, it would be extremely useful if we knew the functions of our candidate genes. For instance, if a gene codes for an enzyme, what type of reaction does this enzyme catalyse? And in which pathways might this reaction take place?

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Exploring the Orphan Crop: Pearl Millet

As an awardee of Global Engage’s Early Career Research grant, we are pleased to announce that Ambika Dudhate will be presenting her research about the drought tolerance in pearl millet in detail at the 6th Plant Genomics and Gene Editing Congress: Europe. It will be a great opportunity to discuss the topic on a large platform.

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Is Palm Oil Sustainable for People?

Palm oil belongs to Elaeis, which is the only genus of Arecaceae family that produces edible oil. The current commercial planting is mainly E. guineensis, (Jacq.) originating from West Africa, selected due to its yield superiority. The cultivations occur throughout the tropical belt, especially in Southeast Asia, Africa and South America. To date, palm oil has become the most important oil crop in the world, accounting for 37% of global vegetable oil production. However, palm oil sustainability is always debated. Is palm oil really sustainable for people? To answer this, some facts are worth pondering.

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Cancer Therapy in the Genomic Era: Barriers and Distractions

Recent step change advances in sequencing technologies have delivered a near-complete lexicon of genomic cancer drivers. In parallel, progress in synthetic chemistry has facilitated the assembly of a broad armamentarium of molecularly-targeted therapies. However, whilst immunotherapy agents have produced notable benefits for subgroups of patients, the impact of molecularly-targeted therapies have been relatively modest.

Further unlocking the undeniable power of genomics in cancer will involve both the systematic removal of barriers and the avoidance of distractions that obscure progress. Both of which are discussed here.

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