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Tag: gut microbiome

Making the microbiome accessible to millennials

In 2017 Lisa and Alanna MacFarlane started The Gut Stuff to bring gut health science and nutritional information together for the millennial generation. We spoke to Lisa about educating consumers and marketing products in gut health.

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Exploring the gut-brain axis in neurodevelopmental disorders

In the last decade, research has well established (relatively speaking) the impact of gut microbiota on host physiology and behaviour. We know that the gut and the brain communicate bidirectionally. The gut-brain axis includes nerval, endocrine and immunologic pathways. What is less well established is whether alterations in gut microbial composition can affect brain structure and function in neurodevelopmental disorders.

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The Future is Bright for Probiotics

I am extremely sceptical of all claims about probiotics. For the last 10 years of running Probiotics.org, companies have been sending me questionable products with extraordinarily impossible to believe claims.

But, after Global Engage’s 4th Probiotic & Prebiotics Congress, here’s what I strongly believe:

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5 Ways Sleep And Microbiome Are Interrelated With Immunity And Cognition

The effect of sleep on the microbiome of the host has been a topic of interest among researchers for the past several years. Studies have yielded opposing results in how short sleep affects the microbiome. While some showed a significant change in Firmicutes to Bacteroidetes ratio, others found no microbial change following short-term sleep restriction.

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Understanding the Role of the Gut Microbiome in NAFLD

NAFLD is the primary contributor to chronic liver disease worldwide with incident rates of 20-30% in western countries and 5-18% in Asia. The discovery of early stage biomarkers for patients with the reversible form of the disease is therefore a research priority. Recent work has shown perturbation of the microbiome and specific microbiome-associated metabolites contribute to the phenotype of NAFLD.

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Discovering the dynamics of prophage induction in the gut ecosystem

The human gut is a complex ecosystem dominated by bacteria and their viruses, i.e. phages. Approximately half of the viruses that reside in our intestine are derived from lysogens, bacteria that contain normally dormant viruses – prophages — in their genome.

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How does Maternal Microbiome composition influence offspring metabolic outcomes?

Professor Margaret Morris is Chair and Head of Pharmacology, School of Medical Sciences, University of NSW. Her research explores the underlying brain mechanisms in epilepsy, obesity, diabetes, and the link between obesity and high blood pressure. We recently asked her about her research into obesity and the microbiome.

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Ask not “what your gut microbiome can do for you”, but “what you can do for your gut microbiome”

Defined health outcomes are increasingly being linked to prebiotic ingredients and supplements. For example, mounting evidence recently led the FDA to issue a qualified health claim regarding the ability of digestion resistant starch to reduce the risk of type 2 diabetes. With the direct annual cost of diabetes recently estimated to be $825B (1), the potential application of prebiotics to reduce disease risk is appealing from both health care and business investment perspectives.

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