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Tag: microbiome

Exploring the gut-brain axis in neurodevelopmental disorders

In the last decade, research has well established (relatively speaking) the impact of gut microbiota on host physiology and behaviour. We know that the gut and the brain communicate bidirectionally. The gut-brain axis includes nerval, endocrine and immunologic pathways. What is less well established is whether alterations in gut microbial composition can affect brain structure and function in neurodevelopmental disorders.

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Culturing the uncultured: isolating human microbial ‘dark matter’

A large fraction of the microorganisms that constitute the human microbiome have remained uncultured. Some of the uncultured microbes have close relatives that have been cultured. However, there are also whole groups of microbes that don’t have relatives in culture.

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How to understand complexity: harness the power of simplicity

One of the most powerful tools in science is the use of simple models that can represent a wide range of other similar systems. 

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The skin safari: looking back on a decade of skin microbiome discoveries

Ahead of the Microbiome and Probiotics R&D and Business Collaboration Forum, Dr Monty Lyman takes us on a journey through the last decade of ground-breaking skin microbiome research, and peers ahead into the next.

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The Future is Bright for Microbiome Metabolites and Drugs Derived From Probiotics

Some of the claims made about Probiotics can be hard to believe, and often even harder to reliably prove. However, the science surrounding the development of these products is exciting, and some of the more extraordinary claims can be quantified.

Here a few examples from some of the presentations at the Microbiome & Prebiotics Series: USA:

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5 Ways Sleep And Microbiome Are Interrelated With Immunity And Cognition

The effect of sleep on the microbiome of the host has been a topic of interest among researchers for the past several years. Studies have yielded opposing results in how short sleep affects the microbiome. While some showed a significant change in Firmicutes to Bacteroidetes ratio, others found no microbial change following short-term sleep restriction.

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Poster Presentations Release: Microbiome Series Europe

Presented at this year’s Microbiome Series: Europe, these poster presentations are now available to download and share with your colleagues.

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Understanding the Role of the Gut Microbiome in NAFLD

NAFLD is the primary contributor to chronic liver disease worldwide with incident rates of 20-30% in western countries and 5-18% in Asia. The discovery of early stage biomarkers for patients with the reversible form of the disease is therefore a research priority. Recent work has shown perturbation of the microbiome and specific microbiome-associated metabolites contribute to the phenotype of NAFLD.

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