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Tag: microbiota

Microbiome Research and Development: An Open Letter From Sarkis Mazmanian

Dear Colleagues,

The concept of the gut-brain axis (GBA) has been around for some time. Yet, the idea that the gut microbiota could regulate the GBA is relatively recent.

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Book Review: Dirt is Good

Dirt Is Good: The Advantage of Germs for Your Child’s Developing Immune System
Authors: Jack Gilbert and Rob Knight (with Sandra Blakeslee)
Publisher: St. Martin’s Press (June 2017)
ISBN-13: 9781250132604

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Monogenic Autoimmune Disorders Display Gut Microbial Dysbiosis

Image credit: NIAID, Flickr, licensed under CC BY 2.0

Autoimmune diseases are an outcome of a dysfunctional immune system. Most common autoimmune diseases, such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), are polygenic autoimmune disorders. However, several monogenic autoimmune disorders have been identified.

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The Big List of Microbiome Companies and Investors

A critical point in any field of research is that of commercialisation; when research builds to the point that the dam bursts, bottlenecks open and opportunities are ripe. 2016 saw the largest peak in microbiome investment since 2012 when the CRISPR-Cas9 ‘instructions’ were published.

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Is the Medical World Ready for Faecal Transplantation as a Therapeutic Option?

The gut microbiota has become a favourite “organ” of the biomedical community, with the number of publications on different aspects of its architecture and function rising exponentially in the last few years. In part fuelled by advances in DNA sequencing technology, multiple studies have been conducted in patients with gastrointestinal (GI) related diseases (IBD, Coeliac, etc.) (1, 2).

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The Uterine Microbiome as a Biomarker for Endometrial Cancer

Image credit: Hey Paul Studios, Flickr, licensed under CC BY 2.0

When asked about her team’s biggest success to date, Marina Walther-Antonio, a Mayo Clinic researcher, highlights the recently published study in Genome Medicine, identifying a unique vaginal microbiome for patients with endometrial cancer. This new discovery could lead to a biomarker for early detection and screening for the disease. It has led to similar research projects to study the impact of the microbiome on ovarian cancer.

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Bacteria in a Bottle: Commercialising a Field in Development

The consumer products industry is built on well-established pillars. It’s a creative and dynamic industry with a clear playbook. While launching a brand or product is not trivial, this general rinse-repeat (pun intended) formula that the market leaders are able to leverage is a big part of why the consumer products industry among the largest on the planet and has continued to grow.

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Innovative Research in Complementary and Alternative Medicines

Sydney, AU, Mon 13 FEB 2017; a television programme on the ABC aired a prime time expose on the Complementary and Alternative Medicines (CAM) industry, with the intent to discredit and warn consumers away from buying products that had no validated proof of working.

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