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  • What does international collaboration mean for you?

    We asked three of our speakers what international collaboration means for them as leaders in their fields.

  • The Biosynthesis of Cannabinoids

    We spoke to Jeremy Friedberg, CSO of  LAVVAN, a company pioneering the biosynthesis of cannabinoids. 

  • The Grass Has Never Been Greener For Engineering Plant Immunity And Resilience

    The wide availability of sequencing technologies has been a rare step-change that has unlocked knowledge in a way nobody in the field could have imagined twenty years ago. Knowledge which could make a considerable contribution to food security in the face of changing climates.

  • How to beneficially modulate vaginal microbiota to optimise women’s health

    Vaginal microbiota plays a crucial role in women’s health and successful reproduction. However, we are just on the verge of discovering the full potential and features of this unique microbial community within women.

Guidelines for Validating Whole Slide Imaging for Diagnostic Purposes

Andrew Evans, speaking at the Digital Pathology & AI Congress USA, described new guidelines he helped to draft for validating whole-slide-imaging for diagnostic purposes. First published in 2013 the guidelines were designed to address the fundamental question, “what needs to be done to validate a whole slide imaging for diagnostic use?”. The review producing the new guidelines was published in May 2021.

Read More

Using the abYsis database for drug discovery

Professor Andrew Martin, UCL, speaking at the 4th Global Pharma R&D AI, Data Science and Informatics Summit, described using the abYsis database and workbench for drug discovery. He showed how it is possible to explore an annotate antibody sequence and structure, including comparisons with observed residue distributions. The database can also aid with humanization by making sequences more human and library design.

Read More

Training AI to predict outcomes for cancer patients

Predicting the outcome of cancer can help the clinical decision-making process related to a patient’s treatment. The potential for Artificial Intelligence (AI) to support this was a key facet of the final keynote speech to the online 7th Digital Pathology and AI Congress: Europe, by Johan Lundin, Research Director at the Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki and Professor of Medical Technology at Karolinska Institutet.

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Multiplex Super-Selective PCR Assays for the Detection and Quantitation of Rare Somatic Mutations

Professor Fred Kramer spoke at the recent Research & Technology Series exploring Flow Cytometry / qPCR & Digital PCR / Liquid Biopsies. During his presentation, he explained how Super Selective primers enable the simultaneous identification and quantitation of rare somatic mutations in routine multiplex PCR assays, while virtually eliminating signals from abundant closely related wild-type sequences.

Read More

AI use in clinical diagnosis

Deep learning tool predicts tumour expression from whole slide images

A deep learning model to predict RNA-Seq expression of tumours from whole slide images was among the industry innovations outlined at the 7th Digital Pathology and AI Congress for Europe. Created by French-American start-up Owkin, the detail of how the company’s HE2RNA model provides virtual spatialization of gene expression was detailed to online delegates by senior translational scientist Alberto Romagnoni who highlighted its use in clinical diagnosis. During his presentation, delegates heard how Owkin has collaborated with doctors, hospitals and academic institutions to develop the tool.

Read More

Machine learning advances diagnostics and prognostics

Computerized image analysis can predict cancer outcomes

The advent of digital pathology is offering a unique opportunity to develop computerized image analysis methods to diagnose disease and predict outcomes for cancer patients from histopathology tissue sections. Such advances can help predict the risk of recurrence, disease aggressiveness and long-term survival, according to a leading expert in the field, Professor Anant Madabhushi from Case Western Reserve University in Ohio.

Read More

Vaginal Microbiota Management and Impact on Women’s Health

Speaking at the 7th Microbiome & Probiotics Business Collaboration Forum, Liisa Lehtoranta explored the future possible directions for vaginal microbiome research.

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Telepathology for second opinion teleconsultation

Speaking at the 2020 Digital Pathology Congress Liron Pantanowiz reviewed why he thought telepathology is the number one application for digital imaging. In this blog, we report what he had to say about telepathology for second opinion teleconsultation.

Read More

Guidelines for Validating Whole Slide Imaging for Diagnostic Purposes

Andrew Evans, speaking at the Digital Pathology & AI Congress USA, described new guidelines he helped to draft for validating whole-slide-imaging for diagnostic purposes. First published in 2013 the guidelines were designed to address the fundamental question, “what needs to be done to validate a whole slide imaging for diagnostic use?”. The review producing the new guidelines was published in May 2021.

Read More

Using the abYsis database for drug discovery

Professor Andrew Martin, UCL, speaking at the 4th Global Pharma R&D AI, Data Science and Informatics Summit, described using the abYsis database and workbench for drug discovery. He showed how it is possible to explore an annotate antibody sequence and structure, including comparisons with observed residue distributions. The database can also aid with humanization by making sequences more human and library design.

Read More

Training AI to predict outcomes for cancer patients

Predicting the outcome of cancer can help the clinical decision-making process related to a patient’s treatment. The potential for Artificial Intelligence (AI) to support this was a key facet of the final keynote speech to the online 7th Digital Pathology and AI Congress: Europe, by Johan Lundin, Research Director at the Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki and Professor of Medical Technology at Karolinska Institutet.

Read More

Multiplex Super-Selective PCR Assays for the Detection and Quantitation of Rare Somatic Mutations

Professor Fred Kramer spoke at the recent Research & Technology Series exploring Flow Cytometry / qPCR & Digital PCR / Liquid Biopsies. During his presentation, he explained how Super Selective primers enable the simultaneous identification and quantitation of rare somatic mutations in routine multiplex PCR assays, while virtually eliminating signals from abundant closely related wild-type sequences.

Read More

AI use in clinical diagnosis

Deep learning tool predicts tumour expression from whole slide images

A deep learning model to predict RNA-Seq expression of tumours from whole slide images was among the industry innovations outlined at the 7th Digital Pathology and AI Congress for Europe. Created by French-American start-up Owkin, the detail of how the company’s HE2RNA model provides virtual spatialization of gene expression was detailed to online delegates by senior translational scientist Alberto Romagnoni who highlighted its use in clinical diagnosis. During his presentation, delegates heard how Owkin has collaborated with doctors, hospitals and academic institutions to develop the tool.

Read More

Machine learning advances diagnostics and prognostics

Computerized image analysis can predict cancer outcomes

The advent of digital pathology is offering a unique opportunity to develop computerized image analysis methods to diagnose disease and predict outcomes for cancer patients from histopathology tissue sections. Such advances can help predict the risk of recurrence, disease aggressiveness and long-term survival, according to a leading expert in the field, Professor Anant Madabhushi from Case Western Reserve University in Ohio.

Read More

Vaginal Microbiota Management and Impact on Women’s Health

Speaking at the 7th Microbiome & Probiotics Business Collaboration Forum, Liisa Lehtoranta explored the future possible directions for vaginal microbiome research.

Read More

Telepathology for second opinion teleconsultation

Speaking at the 2020 Digital Pathology Congress Liron Pantanowiz reviewed why he thought telepathology is the number one application for digital imaging. In this blog, we report what he had to say about telepathology for second opinion teleconsultation.

Read More

Why haven’t microbial products been more widely adopted by farmers?

This is a question that drives me each day. Microbial products have been around for a long time; starting with rhizobium in legumes, dating back 125 years. Yet, in the United States, rhizobium inoculants have not been widely adopted by soybean farmers – some indicate less than 15% use overall in the United States. Why?

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From Consortia to Recombinants: opportunities and challenges facing the next generation of microbials

In this blog post I will discuss two themes that I see driving the next generation of live microbe biologicals for agriculture. These are the rational design and delivery of pairs or consortia (which I will define as more than two microbes) and the commercialization of engineered strains.

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What does international collaboration mean for you?

The present COVID-19 crisis has demonstrated the vital need for knowledge sharing across the global science community. We asked three of our speakers what international collaboration means for them as leaders in their fields.

Read More

The Biosynthesis of Cannabinoids

We recently spoke to Jeremy Friedberg, CSO of  LAVVAN, a company pioneering the biosynthesis of cannabinoids. The conversation was recorded as a podcast, which can be found here.

Read More

The grass has never been greener for engineering plant immunity and resilience

Scientific research is always working at the frontiers of knowledge, but plant genomics technologies have had a dramatic impact on plant science even by our standards. The wide availability of sequencing technologies has been a rare step-change that has unlocked knowledge in a way nobody in the field could have imagined twenty years ago. Knowledge which could make a considerable contribution to food security in the face of changing climates.

Read More

New Breeding Techniques: cloning major resistance genes in cereals

Advances in breeding techniques for cereal crops will be a focus at the 8th Plant Genomics and Gene Editing Congress: USA. We asked Burleigh Dodds, an agricultural science publisher, to share an extract from one of their recent publications, ‘Advances in breeding techniques for cereal crops’.

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Plant biotech in Europe: Present and future

Marcel Kuntz is a panellist for the panel discussion on the regulatory landscape for plant biotechnology at the 8th Plant Genomics & Gene Editing Congress: Europe. Here he provides us with some background for the discussion.

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Using genome editing technology within a systems biology approach to understand plant immunity

Interested in systems biology, omics technology, and plant bioinformatics? Catch up with one of our speakers from the 8th Plant Genomics and Gene Editing Congress: Europe, Professor Kristina Gruden…

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Multiplex and high fidelity: the potential of qPCR

Ahead of the qPCR & Digital PCR Congress, we sat down with David Zhang to talk about his work with PCR as a diagnostic platform.

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Examining Blockchain Systems & Designing Smart Contracts

The blockchain has the potential to enable the collaboration between patients, researchers, and care providers to provide individualised care for patients, but how can this technology be harnessed in a practical way?

This was one of the key questions that was asked at the Blockchain in Healthcare Congress and we had the pleasure of welcoming an array of expert speakers from pharma, academia, and industry to provide the answer.

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The role of extrinsic motivation in sports and physical activity

Motivation is one of the most significant psychological concepts in many areas of life – from work and education to achieving personal goals. In sports and physical activity, motivation plays an especially important part due to the fact that, to millions of people worldwide, staying fit and active is not an obligation or a professional prerequisite, but rather a personal goal. Blockchain technology, together with elements of gamification, may actually help people achieve this goal.

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Conciliating Blockchain and GDPR

Aurélie Bayle is a Data Protection Officer at be-ys: a role she considers to be at the heart of the new legal framework for any company.

Before GDPR came into effect on 25th May 2018, she was working towards global compliance, which involved completing all the steps given by the Article 29 Data Protection Working Party, an advisory board made up of a representative from the data authority of each EU Member State, the European Data Protection Supervisor, and the European Commission. Her duties have included auditing the structures and processes, preparing the data protection impact assessments, checking the compliance of processing activities, analysing the risks of the processing in the medical area, preparing new processes and policies about data protection, and asking data processors about their own compliance.

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When Blockchain Meets the Right to be Forgotten: Technology Versus Law

Over the past few years, the popularity of the blockchain and cryptocurrencies has increased and has reached important notoriety, not only in scientific and IT journals, but also in the media. Although there are many kinds of cryptocurrencies in circulation nowadays, the most popular is Bitcoin.

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Supporting Blockchain Startups: An Open Letter from Katherine Merton

Dear colleagues,

The blockchain technology market is expected to grow to 2.3 billion US dollars by 2021, from 339.5 million US dollars in 2017. [1] With an annual growth rate of 61.5%, it is one of the fastest growing technologies in the healthcare industry.

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The Big List of Microfluidics Companies & Investors

The microfluidic-based devices market has been growing since 2014 due to the increasing point of care testing demand and the miniaturisation of microfluidic chips. 

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What will we do with all this data?

The amount of data we are creating every day has increased exponentially to match the rise in use of smart and connected devices. The internet of things has connected every aspect of our lives to the digital realm: most of these devices operate by tracking your habits, movements, preferences, voice, and more, then logging those habits online. Specifically, the collection of health data has become abundant, because most people now have or wear some sort of device to track daily patterns, steps, cycles, and more. Even our phones often default to track these things for us, whether we choose to enable the function or not.

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