Poster Presentations Release: Biologics and Biosimilars
Posted 27th July 2018 by Jane Williams
Presented at the 4th Biologics & Biosimilars Congress, these poster presentations are now available to download and share with your colleagues.
Round-Up of Top Biologics News
Posted 18th July 2018 by Jane Williams
With new discoveries and developments in Asthma, Diabetes and Cancer, there has been some interesting news to catch up on this month. Take a look at the list below to find out more:
Biologics Congress Europe – Slide release
Posted 6th June 2018 by Jane Williams
Presented at the 4th Biologics & Biosimilars Congress, these free slides are now available to download and share with your colleagues.
Antibody Drug Conjugates: Bioanalytical Assay Challenges and Strategies
Posted 8th January 2018 by Jane Williams
Antibody-drug conjugates (ADCs) combine the high specificity of a monoclonal antibody (mAb) for a target antigen with the highly potent cytotoxic activity of small-molecule drugs. Although the concept behind ADCs is relatively simple, the successful design and development of ADCs is a complex task. Similar to other biotherapeutics, the understanding of Pharmacokinetics (PK), Pharmacodynamics (PD), and Absorption, Distribution, Metabolism, and Excretion (ADME) properties of ADCs is critical for their successful development.
Presentation Slide Release: Biologics Discovery and Development
Posted 9th October 2017 by Jane Williams
Presented at the 3rd Biologics and Biosimilars Congress, these 3 sets of slides are available to download and share with your colleagues.
Developing and Manufacturing Innovative Biologics: Obstacles and Opportunities
Posted 13th September 2017 by Jane Williams
In this 30 minute presentation, Ralf Schumacher discusses developing and manufacturing biologics. Translating discovery knowledge into process design, technology upgrading and gated development paradigms are explored.
Assays in clinical trials and pharmacovigilance
Posted 27th January 2017 by Jane Williams
Assays are crucial during pre-clinical and clinical trials, and for pharmacovigilance. By this stage, the molecule has already been fully profiled with a mechanism of action, and efficacy and safety are now being assessed in vivo.
The pivotal role of assays in biologic and biosimilar discovery and development
Posted 16th January 2017 by Jane Williams
The quality, accuracy and reliability of assays is particularly critical when developing biologics and biosimilars. Assays for biologics are more complicated than for small molecules, often relying on assays which provide relative measures in contrast to the more absolute measurements gained from standard crystallisation or purity profiles.