Sarkis K. Mazmanian
Luis & Nelly Soux Professor of Microbiology, Division of Biology & Biological Engineering, California Institute of Technology, USA
When
19th-20th Oct 2023
Where
San Diego, CA
Marriott La Jolla
Open Letter:
Human exposure to most bacteria does not result in disease, but rather mammals are colonized for life with 100 trillion indigenous bacteria in a symbiotic relationship that contributes to human health. Indeed, the microbiome regulates the development and function of the immune, metabolic, and nervous systems. The mechanistic basis for how commensal microbes influence health and disease remains incompletely understood, but a revolution is currently underway to deepen our comprehension of the microbiota and its influence on human biology.
Our laboratory has shown that specific molecules produced by gut bacterial communities enter the circulation and travel to the brain, and mediate behavioral abnormalities, motor deficits, neuro-inflammation, and brain pathologies. We have discovered that gut bacteria regulate symptoms and pathophysiology of inflammatory bowel disease (IBD), autism spectrum disorder (ASD) and Parkinson’s disease (PD) in animal models, and some of this work is now being translated to humans.
I am delighted to be giving the opening keynote address at the Microbiome & Probiotic R&D & Business Collaboration Forum: USA. Speakers will be showcasing their amazing work that has uncovered mechanisms of interaction between beneficial bacteria and a range of health conditions. Some of these research programs are on the doorstep of, or already in, clinical trials with the potential of creating revolutionary therapeutics to treat human diseases.
I look forward to presenting the talk entitled “Gut-derived Metabolites in a Mouse Model of Anxiety and Autism Spectrum Disorder” on October 19.
See you in San Diego!
Sarkis Mazmanian
Featured speakers:
This program is designed to create a collaborative environment in which delegates can forge enduring relationships across the full range of microbiome and probiotic research. In 2023 you can:
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San Diego Marriot La Jolla
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