6th Dec 2021
Start @ 17:05
Date: 6 December 2021
Duration: 50 minutes
Registration fee: Complimentary access
The MIQE Guidelines: How to get the most out of your molecular measurements
• Control the whole workflow from sampling to data analysis.
• Work according to the MIQE and dMIQE guidelines and the new Technical Specifications and Standards for Molecular in vitro diagnostic examinations by the European Committee for standardization (CEN) and the International Organization for Standardization (ISO).
• Sampling, storage, transportation and isolation of nucleic acids and proteins from biofluids and tissue samples.
• Procedures and protocols for RNA, DNA and protein isolation.
• Quality assessment of RNA, DNA and proteins.
Why MIQE guidelines?
The MIQE and dMIQE guidelines help researchers presenting qPCR and dPCR results in scientific publications and teach reviewers what to request in quality manuscripts.
Why Quality Control of the Pre-analytical phase?
The sampling, handling and storage of samples affects all downstream applications and the final analysis result. Within the European projects SPIDIA(4P), the pre-analytical phase was studied and factors impacting the analytical test results were identified. It was concluded that in many processes the dominant contribution to the total error in the testing process is from the pre-analytical phase.
Why CEN/ISO Technical Specifications and standards?
These specifications were produced to achieve reliable and robust sample handling and preparation in a standardized way to ensure measured data are of high quality and comparable across laboratories. The new guidelines are particularly relevant for accredited laboratories but are also valuable for research, where procedures are standardized, and data compared. The workshop introduces the new Technical Specifications and guidelines and brings them into context for smooth implementation in routine laboratory procedures.
All course participants will receive free license for the GenEx software used in workshop exercises to validate and analyze data.
Who should attend?
• Quality managers at medical, diagnostic and research laboratories
• Laboratory personnel at medical, diagnostic labs and research laboratories
• Biobank personnel
• Managers and researchers coordinating or performing biomarker studies and trial.