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Tag: cancer

Dynamic Microenvironments: Finding the right cancer therapy

With so many promising cancer therapies emerging from research labs, a key challenge for biomedical researchers is to develop tools that accurately predict treatment efficacy against a patient’s specific cancer, thereby avoiding subjecting the patient to a trial and error process to find the best drug.

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Improving cancer diagnosis in rural Sub-Saharan Africa with digital pathology

Cancer is now considered a major public health problem in many Sub-Saharan African countries. It is estimated that 650,000 new cases of cancer are registered in Africa annually. The mortality related to cancer is also higher compared to western countries. It is estimated that 510,000 death related to cancer occur annually in Africa.

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The Uterine Microbiome as a Biomarker for Endometrial Cancer

Image credit: Hey Paul Studios, Flickr, licensed under CC BY 2.0

When asked about her team’s biggest success to date, Marina Walther-Antonio, a Mayo Clinic researcher, highlights the recently published study in Genome Medicine, identifying a unique vaginal microbiome for patients with endometrial cancer. This new discovery could lead to a biomarker for early detection and screening for the disease. It has led to similar research projects to study the impact of the microbiome on ovarian cancer.

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Cross-Cultural Research into Microbiome Therapeutics for Cancer

While microbiome therapeutics to support healthy gut function have garnered the lion’s share of attention, exciting approaches to oncology and anti-inflammatory therapeutics presage a new golden age for drug development, akin to the early commercialisation of chemically synthesised antibiotics from soil biofilms in the mid-20th century.

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Aflatoxin Binding by Probiotic Bacteria

The term ‘probiotic’ comes from the Greek words ‘προ’ and ‘βιοτος’, which mean ‘for life’. In 1953, the ‘probiotic’ term was introduced by Kollath as organic and inorganic supplements necessary to restore health to patients suffering a form of malnutrition resulting from eating too much highly refined food (Hamilton-Miller et al., 2003).

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Synthetic Biology and Cancer Treatment: Bottlenecks to Translation

Karmella Haynes, at the Arizona State University, is one of the first synthetic biologists to engineer chromatin. It is a development that could ultimately treat diseases like cancer, through enabling large-scale changes in gene expression.

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