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Tag: drug discovery

Without challenge, there is no change – the move to precision medicine

I don’t need to tell you that pharma has changed, that it is still changing at speed, or that change is the new normal. I don’t need to tell you because you − more than anyone else − already know. The passing of the blockbuster era has caused uncertainty. Without the superstar drugs of old, where does the industry go next? It’s a serious challenge, but without challenge, there is no change. The answer, of course, is the scalar shift from blockbuster generic to precision medicine specific.

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The Future of AI: A Q&A with Brandon Allgood

Brandon Allgood is the Chief Technology Officer at Numerate, as well as a co-founder. In addition to being responsible for the development of Numerate’s cloud-based machine learning platforms, Brandon runs the software & data science teams, and is the technical lead on all of the companies internal drug programs, as well as external collaborations.

Here, Brandon talks about what he thinks the future holds for AI and machine learning:

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Pricing Pressure, Payer Perspectives and Innovative Diagnostic Platforms

We spoke to Alex Bastian about how he got started in precision medicine, where he sees it going and how he intends to use real world evidence to unlock the potential around personalised approaches to drug development:

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Large-Scale Genetics Research: Q&A with Aris Baras

With genetic data making headlines, Aris Baras reflects on how genetic research can further advancements in medicine and delves into how his team’s work on large-scale approach is paving the way for new discoveries and enhanced patient care.

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Accelerating the Medicinal Chemistry Design Cycle

MedChemNet and Future Medicinal Chemistry editors Jasmine Harris and Ben Walden interviewed Emma Parmee from Merck & Co at the Global Medicinal Chemistry and GPCR Summit.

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Big Data, Informatics and Pharma: An Open Letter From Vaibhav Narayan

Dear colleagues,

Therapeutic interventions have traditionally been developed for patients with established pathologies and overt clinical symptoms. Many diseases however, are not tractable in later stages and therefore therapies are needed that intervene earlier in the disease continuum.

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Manhunting high-value targets in cancer combat

Cancer poses a formidable challenge to public health in modern society. In duelling rituals, the challenged party is usually given the choice of weapons, and possibilities are numerous. Knowing the weaknesses of your opponent is key to combat strategies and weapon selection.

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Big data, knowing and AI: do they influence drug discovery?

The quest for magic bullets started with Paul Ehrlich. He wanted to target the syphilis bacteria without harming the patients, which led to Salvarsan. Ehrlich was a foundational thinker, and we owe him modern concepts such as receptor and pharmacophore. His impact on the field – seeking the ideal molecules – pervades drug discovery.

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