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Tag: IHC

Digital Pathology in Drug Development: Opportunities and Challenges

We recently caught up with Dr Olulanu Aina, Scientific Director and Veterinary and Toxicological Pathologist at Janssen, about digital pathology applications in drug discovery...

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How Beneficial is Digital Pathology for the Laboratory Administrator?

Whether in a research or clinical lab, digital pathology holds a great deal of promise for all stakeholders. Earlier this year, a digital pathology platform obtained FDA clearance for whole slide imaging, thereby increasing both awareness and applicability of digital pathology. It may, however, be difficult for hospitals and laboratories to justify the acquisition costs of digital pathology platforms if one only looks on the surface. Matt Houliston from Definiens looks at the workflow and economic benefits of adopting digital pathology beyond the perhaps more obvious clinical benefits.

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Process Control for Immunohistochemistry Staining Procedures

An extensively used technique for evaluating the expression of tissue antigens and their behaviour is known as immunohistochemistry (IHC). In this technique, the primary antibody raised against the specific antigen and a secondary antibody against the primary one is used for detecting specific targets of clinical relevance. IHC has the greatest impact on diagnostic pathology compared to any other technique. Although modern methods of flow cytometry and molecular diagnosis have also contributed enormously, IHC still remains the most relevant solution for various pathological diagnostic problems.

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