Gut Microbiome analysis – Getting it right
Posted 8th March 2019 by Joshua Sewell
The cascade of new discoveries relating health and disease to our gut microbiome has spurred the notion that we now find ourselves in the middle of a “microbiome revolution”. Just to mention some recent examples, mechanisms have been demonstrated for gut bacteria contributing to Parkinson’s disease,[1] determining response to immune checkpoint inhibitor cancer therapy,[2] and even autistic behavior when fecal material from autistic children was transplanted into mice.[3]
How does Maternal Microbiome composition influence offspring metabolic outcomes?
Posted 27th February 2019 by Joshua Sewell
Professor Margaret Morris is Chair and Head of Pharmacology, School of Medical Sciences, University of NSW. Her research explores the underlying brain mechanisms in epilepsy, obesity, diabetes, and the link between obesity and high blood pressure. We recently asked her about her research into obesity and the microbiome.
Microbiome linked to depression in a groundbreaking Benelux study
Posted 19th February 2019 by Joshua Sewell
This article is republished with kind permission from Biovox. The original article can be found here.
The microbiome had been at the forefront of a lot of research and news in the past few years. Now, a new study published in Nature Microbiology has linked specific microbiome changes with depression and quality of life. The largest of its kind to-date, the research was made possible by over 2000 participants from the Flemish Gut Flora Project and the Dutch LifeLines DEEP project. The results may lead to novel therapies for people suffering from this debilitating mental illness.
Harnessing the power of RNA for a healthy gut microbiome
Posted 13th February 2019 by Joshua Sewell
I was a scientist at Los Alamos National Lab in the US when I identified a science-based personalized diet that completely cured my early onset arthritis. I realized that the gut microbiome would play a central role in personalized nutrition and redirected all my science projects towards it. We desperately needed better technology for analysing the gut microbiome and metatranscriptomics offers the best value. It is better than 16S or metagenomic sequencing in two important aspects:
The gut-brain axis: a new leverage to improve brain conditions
Posted 18th January 2019 by Jane Williams
Recent progress in science pinpoints that the gut-brain axis may be modulated by a class of probiotics called psychobiotics. These progresses shed lights on a new area of research and new ways to treat a broad spectrum of complex central nervous system diseases.
A microbiome solution for type 1 diabetes?
Posted 28th December 2018 by Jane Williams
This article is republished with kind permission from Biovox. The original article can be found here.
Few things unite us the way trying to help a sick child does. Children living with the burden of type 1 diabetes (T1D) is just such a case. The desire to help young patients has galvanized a global effort, the TEDDY study, to understand what causes the disorder and pave the way for effective interventions. A number of analyses emerging from TEDDY are now bringing into focus the role of the microbiome in T1D. We now ask the question: could the microbiome be the key to intercepting and preventing T1D?
The Best Microbiome and Probiotics Articles of 2018
Posted 24th December 2018 by Jane Williams
2018 has been another big year for the microbiome and probiotics. Investment is at an all-time high with the global probiotics market expected to grow with a compound annual growth rate of 6.5% over the forecast period of 2018-2024, while the microbiome market is predicted to grow from $235.8 million in 2018 to $521.23 million by 2022. [1][2]
Biobanking, Therapeutics & Probiotics in Microbiome Research
Posted 19th December 2018 by Jane Williams
As the world becomes increasingly aware of the important role that different bacterial ecosystems play with regards to human and animal health, there is a growing wealth of research coming out of the microbiome industry. Kristina Campbell & Marilyn White, of KC Microbiome, conducted these interviews at the Microbiome R&D and Business Collaboration Forum: USA.