Digital PCR: Possibilities & Opportunities
Posted 23rd April 2018 by Jane Williams
The Digital PCR track at the 4Bio Summit covered the benefits and future development of dPCR, comparisons between dPCR and qPCR and other technologies such as NGS, strategies to convert to a dPCR platform and applying the technology to precision medicine.
If you weren’t able to attend the 4Bio Summit, enjoy these free slides from Ward De Speigelaere, Anthony Magliocco and Nasrin Sarafan-Vasseur.
The Development and Commercialisation of Robust Circulating DNA & RNA Tests
Posted 21st March 2018 by Jane Williams
Precision medicine in oncology requires matching each patient with treatment personalised to their genes and often the proteomic profile of their cancer. Liquid biopsies continue to gain grounds as a tool for diagnostic testing in oncology.
Highlights From The 4th Global Precision Medicine & Biomarkers Leaders Summit
Posted 21st February 2018 by Jane Williams
With just 3 months to go until the Precision Medicine & Biomarkers Leaders Summit: USA, we have taken some time to reflect on the Euopean Precision Medicine & Biomarkers Leaders Summit that took place in Munich in September.
The Development and Application of CRISPR-Cpf1
Posted 20th December 2017 by Jane Williams
Genome editing is slowly causing, or has perhaps already caused, a paradigm shift in the world of agriculture and in plant genomics in general. The ability to precisely and easily edit genes has never been as widespread before as it is now. The technology is causing a momentous shift towards using genome editing to not only validate gene function but also to create better crop varieties for the sustenance of a growing human population.
Molecular Diagnostics for the Point of Care
Posted 5th July 2017 by Jane Williams
Here, we use the term molecular diagnostics to refer to tests that detect the presence of specific nucleic acids in a clinical specimen such as blood, urine, faeces, saliva, and tissue. These nucleic acids serve, among other things, as biomarkers for the presence of infection-causing pathogens (e.g., DNA and/or RNA from bacteria, virus, and/or parasites); diseases such as cancer (characterised by mutant alleles), and genetic abnormalities.
Applications of microfluidics in the real world
Posted 13th March 2017 by Jane Williams
We examine some of the newest applications of microfluidics, including for environmental and clinical detection using paper-based devices, for detection of cancer markers using droplet digital microfluidics, and for assisted-reproductive technology.