Posted 12th October 2018 by Jane Williams
Having a powerful set of tools is essential in life science research so we’ve compiled the best free platforms for genetic engineers, molecular and synthetic biologists.
Posted 28th November 2017 by Jane Williams
Are you tired of secondary structures limiting the synthesis of your gene? Researchers trying to synthesise long (>2.5 kb) or complex GC/AT rich genes often encounter problems during synthesis due to the formation of secondary structures within the DNA.
With these 5 steps, it no longer needs to be an issue.
Posted 22nd November 2017 by Jane Williams
Synthetic biology holds much promise. Researchers have been working toward using techniques to create new valuable products such as novel therapeutics and drugs, biorenewable fuels, and new biochemicals and biomaterials. It requires a multidisciplinary effort – it calls for biologists, chemists, engineers, software developers (STEM disciplines) to collaborate on finding ways to understand how genetic parts work together, and then combine them to produce useful applications.
Posted 12th October 2017 by Jane Williams
Microbial ecology, our understanding of what determines the robustness and community dynamics of microbial consortia, and synthetic biology, the art of engineering microorganisms to perform particular physiological or metabolic functions, are rapidly becoming allies in the race to develop novel therapeutic strategies in the microbiome space.
Posted 6th October 2017 by Jane Williams
Since the minimal cell idea was proposed by Max Delbruck and his Phage School colleagues in the 1930s, biologists have sought to build a cell that encodes only the minimum set of genes necessary for life. Such a minimal cell could be used to investigate the first principles of cellular life.
Posted 8th September 2017 by Jane Williams
Isn’t it frustrating when you follow a great piece of research back to the publisher, but can’t read it? We’ve compiled 7 of the best synthetic biology journal articles of August and better yet, they’re open access.
Posted 28th July 2017 by Jane Williams
Image credit: Fdardel, Wikimedia Commons, licensed under CC BY-SA 3.0
Georg Fritz is an Independent Group Leader at the LOEWE Center for Synthetic Microbiology, Philipps-University Marburg. We caught up with Georg ahead of 4Bio.
Posted 19th July 2017 by Jane Williams
Although the messenger RNA (mRNA) and its roles in the cell were discovered more than half a century ago, it took more than four decades to consider its uses as biologics for human therapeutics. Nowadays, synthetic mRNA, produced in vitro by various enzymatic and non-enzymatic processes, is broadly used in vaccination, immunotherapeutics and even transient gene compensation.